21 CFR Part 73: Listing of Color Additives Exempt from Certification
Part 73 of title 21 runs to 129 sections across 4 subparts, and sits in subchapter A, General. Every section is reproduced in full and is current to 2026-09-10.

- Sections
- 129
- Subparts
- 4
- Words of regulation
- 29,326
- Current to
- 2026-09-10
Subpart A: Foods
- 73.1 Diluents in color additive mixtures for food use exempt from certification8
- 73.30 Annatto extract10
- 73.32 Antarctic krill meal20
- 73.35 Astaxanthin10
- 73.37 Astaxanthin dimethyldisuccinate20
- 73.39 xxx0
- 73.40 Dehydrated beets (beet powder)6
- 73.50 Ultramarine blue5
- 73.69 Butterfly pea flower extract11
- 73.70 Calcium carbonate9
- 73.75 Canthaxanthin16
- 73.80 Calcium phosphate15
- 73.85 Caramel11
- 73.90 β-Apo-8′-carotenal8
- 73.95 β-Carotene6
- 73.100 Cochineal extract; carmine9
- 73.125 Sodium copper chlorophyllin15
- 73.140 Toasted partially defatted cooked cottonseed flour6
- 73.160 Ferrous gluconate5
- 73.165 Ferrous lactate5
- 73.167 Galdieria extract blue10
- 73.168 Gardenia (genipin) blue13
- 73.169 Grape color extract6
- 73.170 Grape skin extract (enocianina)8
- 73.185 Haematococcus algae meal10
- 73.200 Synthetic iron oxide11
- 73.225 Jagua (genipin-glycine) blue11
- 73.250 Fruit juice5
- 73.260 Vegetable juice5
- 73.275 Dried algae meal10
- 73.295 Tagetes (Aztec marigold) meal and extract13
- 73.297 Myoglobin8
- 73.300 Carrot oil6
- 73.315 Corn endosperm oil8
- 73.340 Paprika5
- 73.345 Paprika oleoresin6
- 73.350 Mica-based pearlescent pigments16
- 73.352 Paracoccus pigment16
- 73.355 Phaffia yeast10
- 73.450 Riboflavin6
- 73.500 Saffron5
- 73.520 Soy leghemoglobin11
- 73.530 Spirulina extract10
- 73.575 Titanium dioxide8
- 73.585 Tomato lycopene extract; tomato lycopene concentrate8
- 73.600 Turmeric5
- 73.615 Turmeric oleoresin6
Subpart B: Drugs
- 73.1001 Diluents in color additive mixtures for drug use exempt from certification4
- 73.1010 Alumina (dried aluminum hydroxide)6
- 73.1015 Chromium-cobalt-aluminum oxide10
- 73.1025 Ferric ammonium citrate9
- 73.1030 Annatto extract5
- 73.1070 Calcium carbonate6
- 73.1075 Canthaxanthin5
- 73.1085 Caramel4
- 73.1095 β-Carotene5
- 73.1100 Cochineal extract; carmine5
- 73.1125 Potassium sodium copper chloropyhllin (chlorophyllin-copper complex)6
- 73.1150 Dihydroxyacetone6
- 73.1162 Bismuth oxychloride6
- 73.1200 Synthetic iron oxide6
- 73.1298 Ferric ammonium ferrocyanide6
- 73.1299 Ferric ferrocyanide6
- 73.1326 Chromium hydroxide green6
- 73.1327 Chromium oxide greens6
- 73.1329 Guanine6
- 73.1350 Mica-based pearlescent pigments9
- 73.1375 Pyrogallol9
- 73.1400 Pyrophyllite6
- 73.1410 Logwood extract8
- 73.1496 Mica6
- 73.1530 Spirulina extract10
- 73.1550 Talc6
- 73.1575 Titanium dioxide5
- 73.1645 Aluminum powder6
- 73.1646 Bronze powder6
- 73.1647 Copper powder6
- 73.1991 Zinc oxide6
Subpart C: Cosmetics
- 73.2030 Annatto4
- 73.2085 Caramel4
- 73.2087 Carmine5
- 73.2095 β-Carotene4
- 73.2110 Bismuth citrate9
- 73.2120 Disodium EDTA-copper5
- 73.2125 Potassium sodium copper chlorophyllin (chlorophyllin-copper complex)6
- 73.2150 Dihydroxyacetone4
- 73.2162 Bismuth oxychloride7
- 73.2180 Guaiazulene6
- 73.2190 Henna5
- 73.2250 Iron oxides5
- 73.2298 Ferric ammonium ferrocyanide4
- 73.2299 Ferric ferrocyanide4
- 73.2326 Chromium hydroxide green4
- 73.2327 Chromium oxide greens4
- 73.2329 Guanine7
- 73.2400 Pyrophyllite4
- 73.2496 Mica4
- 73.2500 Silver6
- 73.2550 Silver nitrate18
- 73.2575 Titanium dioxide4
- 73.2645 Aluminum powder4
- 73.2646 Bronze powder4
- 73.2647 Copper powder4
- 73.2725 Ultramarines5
- 73.2775 Manganese violet5
- 73.2991 Zinc oxide4
- 73.2995 Luminescent zinc sulfide9
Subpart D: Medical Devices
- 73.3100 1,4-Bis[(2-hydroxyethyl)amino]-9,10-anthracenedione bis(2-methyl-2-propenoic)ester copolymers5
- 73.3105 1,4-Bis[(2-methylphenyl)amino]-9,10-anthracenedione5
- 73.3106 1,4-Bis[4-(2-methacryloxyethyl)phenylamino]anthraquinone copolymers5
- 73.3107 Carbazole violet5
- 73.3110 Chlorophyllin-copper complex, oil soluble6
- 73.3110a a Chromium-cobalt-aluminum oxide5
- 73.3111 Chromium oxide greens5
- 73.3112 C.I. Vat Orange 15
- 73.3115 2-[[2,5-Diethoxy-4-[(4-methylphenyl)thiol]phenyl]azo]-1,3,5-benzenetriol7
- 73.3117 16,23-Dihydrodinaphtho[2,3-a:2′,3′-i] naphth [2′,3′:6,7] indolo [2,3-c] carbazole-5,10,15,17,22,24-hexone5
- 73.3118 N,N′-(9,10-Dihydro-9,10-dioxo-1,5-anthracenediyl) bisbenzamide5
- 73.3119 7,16-Dichloro-6,15-dihydro-5,9,14,18-anthrazinetetrone5
- 73.3120 16,17-Dimethoxydinaphtho [1,2,3-cd:3′,2′,1′-lm] perylene-5,10-dione5
- 73.3121 Poly(hydroxyethyl methacrylate)-dye copolymers16
- 73.3122 4-[(2,4-dimethylphenyl)azo]-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one5
- 73.3123 6-Ethoxy-2-(6-ethoxy-3-oxobenzo[b]thien-2(3H)-ylidene) benzo[b]thiophen-3 (2H)-one5
- 73.3124 Phthalocyanine green5
- 73.3125 Iron oxides5
- 73.3126 Titanium dioxide5
- 73.3127 Vinyl alcohol/methyl methacrylate-dye reaction products12
- 73.3128 Mica-based pearlescent pigments5
- 73.3129 Disodium 1-amino-4-[[4-[(2-bromo-1-oxoallyl)amino]-2-sulfonatophenyl]amino]-9,10-dihydro-9,10-dioxoanthracene-2-sulfonate5
Read 21 CFR part 73 at the eCFR · All of 21 CFR for food safety
Questions
- What does 21 CFR part 73 cover?
- 21 CFR part 73 is Listing of Color Additives Exempt from Certification. It runs to 129 sections across 4 subparts and sits in subchapter A of chapter I, General.
Every section of part 73 is a clause somebody has to produce evidence for at their next audit. Krolda maps supplier documents to the clause they satisfy in FSSC 22000, IFS Food and 21 CFR 117, and routes the corrective action when the evidence is missing.
Early accessRecall records come from the openFDA food enforcement API, published by the U.S. Food and Drug Administration in the public domain. Krolda adds the hazard classification and the clause mapping; neither is an FDA determination. Always check the FDA notice before acting on a recall.