21 CFR Part 500: General
Part 500 of title 21 runs to 22 sections across 5 subparts, and sits in subchapter E, Animal Drugs, Feeds, and Related Products. Every section is reproduced in full and is current to 2026-09-10.
- Sections
- 22
- Subparts
- 5
- Words of regulation
- 5,660
- Current to
- 2026-09-10
Subpart B: Specific Administrative Rulings and Decisions
- 500.23 Thermally processed low-acid foods packaged in hermetically sealed containers1
- 500.24 Emergency permit control1
- 500.25 Anthelmintic drugs for use in animals4
- 500.26 Timed-release dosage form drugs4
- 500.27 Methylene blue-containing drugs for use in animals8
- 500.29 Gentian violet for use in animal feed1
- 500.30 Gentian violet for animal drug use1
- 500.45 Use of polychlorinated biphenyls (PCB's) in the production, handling, and storage of animal feed11
- 500.46 Hexachlorophene in animal drugs5
- 500.50 Propylene glycol in or on cat food1
Subpart C: Animal Drug Labeling Requirements
Subpart D: Requirements for Specific Animal Drugs
Subpart E: Regulation of Carcinogenic Compounds Used in Food-Producing Animals
Subpart F: Methods for Detection of Residues of Carcinogenic Compounds Used in Food-Producing Animals
Read 21 CFR part 500 at the eCFR · All of 21 CFR for food safety
Questions
- What does 21 CFR part 500 cover?
- 21 CFR part 500 is General. It runs to 22 sections across 5 subparts and sits in subchapter E of chapter I, Animal Drugs, Feeds, and Related Products.
Every section of part 500 is a clause somebody has to produce evidence for at their next audit. Krolda maps supplier documents to the clause they satisfy in FSSC 22000, IFS Food and 21 CFR 117, and routes the corrective action when the evidence is missing.
Early accessRecall records come from the openFDA food enforcement API, published by the U.S. Food and Drug Administration in the public domain. Krolda adds the hazard classification and the clause mapping; neither is an FDA determination. Always check the FDA notice before acting on a recall.