What does 21 CFR part 178 cover?

21 CFR part 178 is Indirect Food Additives: Adjuvants, Production Aids, and Sanitizers. It runs to 47 sections across 3 subparts and sits in subchapter B of chapter I, Food for Human Consumption.

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21 CFR Part 178: Indirect Food Additives: Adjuvants, Production Aids, and Sanitizers

Part 178 of title 21 runs to 47 sections across 3 subparts, and sits in subchapter B, Food for Human Consumption. Every section is reproduced in full and is current to 2026-09-10.

Sections: 47
Subparts: 3
Words of regulation: 28,286
Current to: 2026-09-10

Subpart B: Substances Utilized To Control the Growth of Microorganisms

Subpart C: Antioxidants and Stabilizers

Subpart D: Certain Adjuvants and Production Aids

Read 21 CFR part 178 at the eCFR · All of 21 CFR for food safety

Questions

What does 21 CFR part 178 cover?: 21 CFR part 178 is Indirect Food Additives: Adjuvants, Production Aids, and Sanitizers. It runs to 47 sections across 3 subparts and sits in subchapter B of chapter I, Food for Human Consumption.

Every section of part 178 is a clause somebody has to produce evidence for at their next audit. Krolda maps supplier documents to the clause they satisfy in FSSC 22000, IFS Food and 21 CFR 117, and routes the corrective action when the evidence is missing.

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Recall records come from the openFDA food enforcement API, published by the U.S. Food and Drug Administration in the public domain. Krolda adds the hazard classification and the clause mapping; neither is an FDA determination. Always check the FDA notice before acting on a recall.