21 CFR Part 172: Food Additives Permitted for Direct Addition to Food for Human Consumption
Part 172 of title 21 runs to 153 sections across 9 subparts, and sits in subchapter B, Food for Human Consumption. Every section is reproduced in full and is current to 2026-09-10.

- Sections
- 153
- Subparts
- 9
- Words of regulation
- 44,203
- Current to
- 2026-09-10
Subpart A: General Provisions
Subpart B: Food Preservatives
- 172.105 Anoxomer8
- 172.110 BHA7
- 172.115 BHT6
- 172.120 Calcium disodium EDTA9
- 172.130 Dehydroacetic acid4
- 172.133 Dimethyl dicarbonate16
- 172.135 Disodium EDTA10
- 172.140 Ethoxyquin2
- 172.145 Heptylparaben4
- 172.150 4-Hydroxymethyl-2,6-di-tert-butylphenol4
- 172.155 Natamycin (pimaricin)3
- 172.160 Potassium nitrate1
- 172.165 Quaternary ammonium chloride combination5
- 172.167 Silver nitrate and hydrogen peroxide solution9
- 172.170 Sodium nitrate10
- 172.175 Sodium nitrite11
- 172.177 Sodium nitrite used in processing smoked chub8
- 172.180 Stannous chloride1
- 172.185 TBHQ5
- 172.190 THBP4
Subpart C: Coatings, Films and Related Substances
- 172.210 Coatings on fresh citrus fruit7
- 172.215 Coumarone-indene resin14
- 172.225 Methyl and ethyl esters of fatty acids produced from edible fats and oils5
- 172.230 Microcapsules for flavoring substances8
- 172.235 Morpholine3
- 172.250 Petroleum naphtha30
- 172.255 Polyacrylamide1
- 172.260 Oxidized polyethylene4
- 172.270 Sulfated butyl oleate5
- 172.275 Synthetic paraffin and succinic derivatives5
- 172.280 Terpene resin5
Subpart D: Special Dietary and Nutritional Additives
- 172.310 Aluminum nicotinate1
- 172.315 Nicotinamide-ascorbic acid complex3
- 172.320 Amino acids26
- 172.325 Bakers yeast protein11
- 172.330 Calcium pantothenate, calcium chloride double salt5
- 172.335 D-Pantothenamide1
- 172.340 Fish protein isolate11
- 172.345 Folic acid (folacin)12
- 172.350 Fumaric acid and salts of fumaric acid6
- 172.365 Kelp1
- 172.370 Iron-choline citrate complex1
- 172.372 N-Acetyl-L-methionine19
- 172.375 Potassium iodide5
- 172.379 Vitamin D24
- 172.380 Vitamin D315
- 172.381 Vitamin D2 bakers yeast6
- 172.382 Vitamin D2 mushroom powder14
- 172.385 Whole fish protein concentrate18
- 172.395 Xylitol1
- 172.399 Zinc methionine sulfate4
Subpart E: Anticaking Agents
Subpart F: Flavoring Agents and Related Substances
- 172.510 Natural flavoring substances and natural substances used in conjunction with flavors3
- 172.515 Synthetic flavoring substances and adjuvants5
- 172.520 Cocoa with dioctyl sodium sulfosuccinate for manufacturing1
- 172.530 Disodium guanylate1
- 172.535 Disodium inosinate3
- 172.540 DL-Alanine1
- 172.560 Modified hop extract13
- 172.575 Quinine1
- 172.580 Safrole-free extract of sassafras5
- 172.585 Sugar beet extract flavor base3
- 172.590 Yeast-malt sprout extract3
Subpart G: Gums, Chewing Gum Bases and Related Substances
Subpart H: Other Specific Usage Additives
- 172.710 Adjuvants for pesticide use dilutions11
- 172.712 1,3-Butylene glycol4
- 172.715 Calcium lignosulfonate3
- 172.720 Calcium lactobionate3
- 172.723 Epoxidized soybean oil7
- 172.725 Gibberellic acid and its potassium salt17
- 172.730 Potassium bromate7
- 172.735 Glycerol ester of rosin3
- 172.736 Glycerides and polyglycides of hydrogenated vegetable oils8
- 172.755 Stearyl monoglyceridyl citrate4
- 172.765 Succistearin (stearoyl propylene glycol hydrogen succinate)4
- 172.770 Ethylene oxide polymer4
- 172.775 Methacrylic acid-divinylbenzene copolymer4
- 172.780 Acacia (gum arabic)5
- 172.785 Listeria-specific bacteriophage preparation12
Subpart I: Multipurpose Additives
- 172.800 Acesulfame potassium6
- 172.802 Acetone peroxides8
- 172.803 Advantame11
- 172.804 Aspartame11
- 172.806 Azodicarbonamide9
- 172.808 Copolymer condensates of ethylene oxide and propylene oxide13
- 172.809 Curdlan15
- 172.810 Dioctyl sodium sulfosuccinate7
- 172.811 Glyceryl tristearate7
- 172.812 Glycine6
- 172.814 Hydroxylated lecithin8
- 172.816 Methyl glucoside-coconut oil ester5
- 172.818 Oxystearin6
- 172.820 Polyethylene glycol (mean molecular weight 200-9,500)33
- 172.822 Sodium lauryl sulfate14
- 172.824 Sodium mono- and dimethyl naphthalene sulfonates8
- 172.826 Sodium stearyl fumarate8
- 172.828 Acetylated monoglycerides6
- 172.829 Neotame12
- 172.830 Succinylated monoglycerides6
- 172.831 Sucralose4
- 172.832 Monoglyceride citrate6
- 172.833 Sucrose acetate isobutyrate (SAIB)9
- 172.834 Ethoxylated mono- and diglycerides7
- 172.836 Polysorbate 6044
- 172.838 Polysorbate 6523
- 172.840 Polysorbate 8032
- 172.841 Polydextrose7
- 172.842 Sorbitan monostearate27
- 172.844 Calcium stearoyl-2-lactylate15
- 172.846 Sodium stearoyl lactylate13
- 172.848 Lactylic esters of fatty acids4
- 172.850 Lactylated fatty acid esters of glycerol and propylene glycol4
- 172.852 Glyceryl-lacto esters of fatty acids3
- 172.854 Polyglycerol esters of fatty acids5
- 172.856 Propylene glycol mono- and diesters of fats and fatty acids3
- 172.858 Propylene glycol alginate16
- 172.859 Sucrose fatty acid esters19
- 172.860 Fatty acids17
- 172.861 Cocoa butter substitute from coconut oil, palm kernel oil, or both oils7
- 172.862 Oleic acid derived from tall oil fatty acids12
- 172.863 Salts of fatty acids6
- 172.864 Synthetic fatty alcohols49
- 172.866 Synthetic glycerin produced by the hydrogenolysis of carbohydrates3
- 172.867 Olestra10
- 172.868 Ethyl cellulose6
- 172.869 Sucrose oligoesters4
- 172.870 Hydroxypropyl cellulose7
- 172.872 Methyl ethyl cellulose7
- 172.874 Hydroxypropyl methylcellulose4
- 172.876 Castor oil5
- 172.878 White mineral oil7
- 172.880 Petrolatum6
- 172.882 Synthetic isoparaffinic petroleum hydrocarbons11
- 172.884 Odorless light petroleum hydrocarbons8
- 172.886 Petroleum wax58
- 172.888 Synthetic petroleum wax6
- 172.890 Rice bran wax3
- 172.892 Food starch-modified10
- 172.894 Modified cottonseed products intended for human consumption15
- 172.896 Dried yeasts1
- 172.898 Bakers yeast glycan9
Read 21 CFR part 172 at the eCFR · All of 21 CFR for food safety
Questions
- What does 21 CFR part 172 cover?
- 21 CFR part 172 is Food Additives Permitted for Direct Addition to Food for Human Consumption. It runs to 153 sections across 9 subparts and sits in subchapter B of chapter I, Food for Human Consumption.
Every section of part 172 is a clause somebody has to produce evidence for at their next audit. Krolda maps supplier documents to the clause they satisfy in FSSC 22000, IFS Food and 21 CFR 117, and routes the corrective action when the evidence is missing.
Early accessRecall records come from the openFDA food enforcement API, published by the U.S. Food and Drug Administration in the public domain. Krolda adds the hazard classification and the clause mapping; neither is an FDA determination. Always check the FDA notice before acting on a recall.